| Rnd | Team | Match Date | Home Team | Result | Away Team |
|---|
| 2 | Second XI | 2000-10-21 | Glenroy Amateurs | def | Murrumbeena |
| 2/99 | | 88 |
| 3 | Second XI | 2000-11-04 | Murrumbeena | lost to | Highett |
| 80
and 5/98 D Murchie 30* | | 5/246 B Hardham 2/84 |
| 4 | Second XI | 2000-11-18 | MHSOB |  | Murrumbeena |
| 238 D Hardham 4/48 M Saunders 2/13 | | 9/282 P Hay 27 D Hardham 137* M Saunders 48 |
| 5 | Second XI | 2000-12-02 | Murrumbeena | lost to | St Johns/St Bedes |
| 4/232 A Wood 116* M Saunders 58 | | 6/243 G Hay 3/33 |
| 6 | Third XI | 2000-12-16 | Murrumbeena | lost to | Mentone |
| 63
and 1/32 | | 167 S Shaw 3/53 J Morton 3/35 P Gyi 2/19 |
| 8 | Second XI | 2001-01-20 | Brighton East | def | Murrumbeena |
| 2/190 | | 7/126 P Hay 41* |
| 9 | Second XI | 2001-02-03 | Murrumbeena | lost to | Hoppers Crossing |
| 9/122 D Hardham 33 G Hay 27 D Murchie 32 | | 8/227 D Tigges 3/40 I Jumar 2/84 |
| 10 | Second XI | 2001-02-10 | Youlden - Parkville | def | Murrumbeena |
| 9/222 J Martin 8/69 | | 51
and 5/180 W Dutton 37 A Wood 45 G Hay 31* JG Banks 34 |
