| Rnd | Team | Match Date | Home Team | Result | Away Team |
|---|
| 1 | Second XI | 2020-11-14 | Hampton | def | Murrumbeena |
| 3/127 | | 123 J Walker 36 |
| 2 | Second XI | 2020-11-21 | Murrumbeena | lost to | Bonbeach |
| 195 T Lamb 44 J Martin 25 | | 2/225 |
| 3 | Second XI | 2020-11-28 | Mordialloc | def | Murrumbeena |
| 7/149 P Gupta 2/33 M Poonia 2/23 | | 57 |
| 7 | Second XI | 2021-01-09 | Bentleigh | def | Murrumbeena |
| 5/182 | | 101 J Martin 27 |
| 9 | Second XI | 2021-01-23 | Bonbeach |  | Murrumbeena |
| 87 N Paranagama 3/12 D Venturoni 2/19 T Fierenzi 3/10 J Harper 2/12 | | 6/132 C Anstee 43 T Dennis 25* |
| 11 | Second XI | 2021-02-07 | Murrumbeena | | Parkdale |
| 5/187 C Anstee 33 J Martin 75* D Venturoni 45 | | 186 N Paranagama 2/32 D Venturoni 4/25 J Harper 2/34 |
| 13 | Second XI | 2021-02-20 | Murrumbeena | lost to | Mordialloc |
| 186 Z Goold 56 J Walker 41 D Venturoni 28 | | 199 Z Goold 2/34 D Venturoni 3/54 N Paranagama 2/18 |
| 14 | Second XI | 2021-02-27 | McKinnon | def | Murrumbeena |
| 185 Z Goold 2/28 D Venturoni 3/33 J Anstee 3/28 P Gupta 2/12 | | 140 C Anstee 36 |
