| Rnd | Team | Match Date | Home Team | Result | Away Team |
|---|
| 1 | First XI | 2020-11-14 | Murrumbeena |  | Hampton |
| 195 X Ross 27 B Hardham 59 | | 7/188 B Kruger 2/33 D Parkinson 4/37 |
| 2 | First XI | 2020-11-21 | Bonbeach | | Murrumbeena |
| 75 B Kruger 5/25 J Handley 2/4 | | 2/76 AR Ross 43* |
| 3 | First XI | 2020-11-28 | Murrumbeena | lost to | South Caulfield |
| 172 B Kruger 55 AR Ross 25 | | 7/175 D Parkinson 2/30 T Kelly 2/31 |
| 4 | First XI | 2020-12-05 | Carnegie | def | Murrumbeena |
| 7/226 B Kruger 2/48 D Parkinson 2/30 M Guruge 2/42 | | 6/91 A Hay 29 B Kruger 27 |
| 5 | Second XI | 2020-12-12 | Murrumbeena | | Mentone |
| 6/144 M Goold 25 J Williams 63 | | 9/143 J Walker 4/19 N Paranagama 2/13 J Harper 2/24 |
| 6 | First XI | 2020-12-19 | Murrumbeena | | Parkdale |
| 9/158 X Ross 28 B Kruger 30 J Handley 40 | | 9/154 B Kruger 3/22 W Kelly 3/28 T Kelly 2/46 |
| 7 | First XI | 2021-01-09 | Murrumbeena | lost to | Bentleigh |
| 207 B Kruger 52 W Kelly 50 J Handley 49 | | 5/249 N Karunarathne 2/42 |
| 9 | Second XI | 2021-01-23 | Bonbeach | | Murrumbeena |
| 87 N Paranagama 3/12 D Venturoni 2/19 T Fierenzi 3/10 J Harper 2/12 | | 6/132 C Anstee 43 T Dennis 25* |
| 10 | Second XI | 2021-01-30 | Murrumbeena | | Bentleigh |
| 6/194 J Williams 133* | | 193 Z Goold 4/30 J Harper 2/28 I Khan 2/45 |
| 11 | First XI | 2021-02-06 | Murrumbeena | lost to | Parkdale |
| 6/183 A Hay 78* AR Ross 26 B Hardham 34 | | 5/184 M Guruge 2/30 |
| 13 | First XI | 2021-02-20 | South Caulfield | def | Murrumbeena |
| 2/185 | | 9/184 A Hay 28 AR Ross 33 W Kelly 51 J Williams 28 |
| 12 | First XI | 2021-02-21 | Murrumbeena | lost to | Beaumaris |
| 132 M Guruge 26 | | 7/149 T Kelly 2/20 N Karunarathne 3/32 |
| 14 | First XI | 2021-02-27 | Murrumbeena | lost to | Carnegie |
| 6/167 A Hay 26 B Kruger 38 J Williams 44 | | 6/170 T Kelly 2/44 |
