| Rnd | Team | Match Date | Home Team | Result | Away Team |
|---|
| 2 | Second XI | 2021-11-20 | Murrumbeena | lost to | Mentone |
| 191 C Anstee 25 J Lockhart 42 | | 5/232 N Paranagama 2/24 |
| 3 | Second XI | 2021-11-27 | Heatherton | def | Murrumbeena |
| 181 Z Goold 2/33 J Anstee 3/13 T Fierenzi 2/26 | | 124 D Venturoni 25 |
| 5 | Second XI | 2021-12-11 | Murrumbeena |  | Mordialloc |
| 1/170 Z Goold 51* J Williams 98* | | 7/166 T Kelly 3/14 |
| 8 | Second XI | 2022-01-15 | Murrumbeena | lost to | Beaumaris |
| 9/189 C Anstee 26 J Walker 60 | | 7/193 Z Goold 2/33 S Hillemacher 2/20 |
| 12 | Second XI | 2022-02-12 | Mordialloc | def | Murrumbeena |
| 207 J Bailey 2/37 A Frangoulis 3/19 T Fierenzi 4/25 | | 193 J Flynn 71 H Zandberg 63 |
| 13 | Second XI | 2022-02-19 | Murrumbeena | lost to | McKinnon |
| 9/178 J Williams 26 A Frangoulis 52 | | 6/181 S Hillemacher 2/27 N Paranagama 2/38 |
