| Rnd | Team | Match Date | Home Team | Result | Away Team |
|---|
| 2 | U17 Friday | 2021-11-19 | Murrumbeena | lost to | Notting Hill-Brandon Park |
| 8/77 | | 2/140 |
| 2 | Second XI | 2021-11-20 | Murrumbeena | lost to | Mentone |
| 191 C Anstee 25 J Lockhart 42 | | 5/232 N Paranagama 2/24 |
| 2 | U17A Sunday | 2021-11-21 | Mazenod OC | def | Murrumbeena |
| 8/112 P Chivers 2/18 S Hawkins 2/25 | | 7/80 C Anstee 27 |
| 3 | U17 Friday | 2021-11-26 | Ashwood | tied | Murrumbeena |
| 5/134 M Girdhar 2/20 J Fairweather 2/4 | | 7/134 J Singh 52 A Mehta 65 |
| 3 | Second XI | 2021-11-27 | Heatherton | def | Murrumbeena |
| 181 Z Goold 2/33 J Anstee 3/13 T Fierenzi 2/26 | | 124 D Venturoni 25 |
| 3 | U17A Sunday | 2021-11-28 | Murrumbeena | lost to | Balwyn |
| 5/124 H Zandberg 53* J Anstee 25 | | 3/158 |
| 4 | U17 Friday | 2021-12-03 | Murrumbeena | lost to | Toorak-Prahran Red |
| 9/124 J Singh 34 | | 5/135 E Daly 2/30 |
| 4 | Second XI | 2021-12-04 | Murrumbeena | tied | Hampton |
| 9/185 A Frangoulis 51 S Hillemacher 34* J Anstee 34 | | 7/185 P Gupta 2/34 S Hillemacher 2/39 |
| 4 | U17A Sunday | 2021-12-05 | Murrumbeena |  | Mt Waverley |
| 1/164 C Anstee 98* S Hillemacher 44* | | 6/112 J Vanderkruk 2/9 R Murphy 2/15 |
| 5 | U17 Friday | 2021-12-10 | Ashwood | def | Murrumbeena |
| 5/164 E Daly 2/19 | | 6/163 H Zandberg 42 A Mehta 61 |
| 5 | Third XI | 2021-12-11 | Bentleigh | def | Murrumbeena |
| 3/169 | | 159 H Zandberg 48* I Khan 27 |
| 6 | U17 Friday | 2021-12-17 | Murrumbeena | lost to | Notting Hill-Brandon Park |
| 6/152 T Kelley 30 J Singh 32 H Zandberg 27 C Anstee 32* | | 1/154 |
| 6 | U17A Sunday | 2021-12-19 | Murrumbeena | lost to | Melbourne High School |
| 5/103 C Anstee 40 | | 3/106 S Hillemacher 2/15 |
| 8 | Second XI | 2022-01-15 | Murrumbeena | lost to | Beaumaris |
| 9/189 C Anstee 26 J Walker 60 | | 7/193 Z Goold 2/33 S Hillemacher 2/20 |
| 7 | U17 Friday | 2022-01-21 | Ashwood | def | Murrumbeena |
| 2/151 | | 6/134 H Zandberg 38 J Ubachs 26* |
| 9 | Third XI | 2022-01-22 | Parkdale United | | Murrumbeena |
| 99 O Hillemacher 2/11 P Chivers 2/32 | | 3/187 S Hawkins 64 D Venturoni 66* |
| 7 | U17A Sunday | 2022-01-23 | Murrumbeena | | Mazenod OC |
| 7/101 H Zandberg 37 J Anstee 34 | | 85 P Chivers 4/17 F Raistrick 2/7 |
| 10 | Second XI | 2022-01-29 | Murrumbeena | lost to | Heatherton |
| 114 | | 9/276 S Hillemacher 4/49 P Chivers 2/61 N Paranagama 2/45 |
| 8 | U17A Sunday | 2022-01-30 | Murrumbeena | lost to | Oakleigh |
| 118 W Parkin 48* | | 6/122 P Chivers 2/24 F Raistrick 2/11 |
| 9 | U17 Friday | 2022-02-04 | Toorak-Prahran Red | def | Murrumbeena |
| 8/131 T Kelley 3/22 J Fairweather 3/12 | | 9/100 H Zandberg 46 |
| 11 | Second XI | 2022-02-05 | Hampton | | Murrumbeena |
| 8/169 D Venturoni 2/18 S Hillemacher 2/36 | | 7/184 A Frangoulis 63 H Zandberg 38 |
| 9 | U17A Sunday | 2022-02-06 | Box Hill | def | Murrumbeena |
| 5/105 P Chivers 2/23 | | 9/102 H Zandberg 52 |
| 10 | U17 Friday | 2022-02-11 | Murrumbeena | | Ashwood |
| 2/136 H Zandberg 55 J Singh 28* | | 7/134 J Singh 2/26 G Nandini 2/8 |
| 12 | Second XI | 2022-02-12 | Mordialloc | def | Murrumbeena |
| 207 J Bailey 2/37 A Frangoulis 3/19 T Fierenzi 4/25 | | 193 J Flynn 71 H Zandberg 63 |
| 11 | U17 Friday | 2022-02-18 | Ashwood | | Murrumbeena |
| 106 E Daly 3/6 | | 1/110 C Anstee 39* H Zandberg 55* |
| 13 | Second XI | 2022-02-19 | Murrumbeena | lost to | McKinnon |
| 9/178 J Williams 26 A Frangoulis 52 | | 6/181 S Hillemacher 2/27 N Paranagama 2/38 |
| 11 | U17A Sunday | 2022-02-20 | Melbourne High School | def | Murrumbeena |
| 7/110 J Vanderkruk 3/9 | | 9/76 |
| 12 | U17 Friday | 2022-02-25 | Murrumbeena | | Toorak-Prahran - Blue |
| 5/194 H Zandberg 108 J Ubachs 27 | | 110 E Daly 2/29 J Fairweather 2/9 F Raistrick 5/24 |
| 14 | Second XI | 2022-02-26 | Murrumbeena | | Bonbeach |
| 274 J Williams 103 H Zandberg 97 | | 222 J Williams 2/28 S Hawkins 2/30 D Venturoni 3/38 S Hillemacher 2/30 |
| 12 | U17A Sunday | 2022-02-27 | Croydon | | Murrumbeena |
| 7/110 J Vanderkruk 2/11 S Hawkins 3/10 | | 1/144 H Zandberg 59 W Parkin 55* |
| 13 | U17 Friday | 2022-03-04 | Glen Waverley | def | Murrumbeena |
| 4/173 T Kelley 2/41 E Daly 2/29 | | 8/100 H Zandberg 25 |
