| Rnd | Match Date | Home Team | Result | Away Team |
|---|
| 1 | 2021-11-13 | Malvern Junior Gold | no play | Murrumbeena |
| 2 | 2021-11-20 | Murrumbeena Blue |  | Murrumbeena |
| 81 T Langham 2/7 D Fitzpatrick 2/4 A Brooks 2/3 | | 2/225 B Bletsas 27 |
| 3 | 2021-11-27 | Murrumbeena | | Mt Waverley Oxley |
| 5/164 | | 97 T Langham 3/3 E Hawkins 3/9 |
| 4 | 2021-12-04 | Toorak-Prahran Colts | | Murrumbeena |
| 80 D Fitzpatrick 3/9 R Krom 2/11 | | 3/186 |
| 5 | 2021-12-11 | Murrumbeena | | Clayton District |
| 9/139 | | 7/107 T Langham 3/14 |
| 6 | 2021-12-18 | Murrumbeena | no play | Toorak-Prahran Red |
| 7 | 2022-01-22 | Murrumbeena | | Murrumbeena Blue |
| 3/145 | | 91 E Hawkins 3/11 A Brooks 2/16 J Carrie 2/12 |
| 8 | 2022-01-29 | Clayton District | | Murrumbeena |
| 111 E Hawkins 2/3 T Langham 3/8 | | 5/134 |
| 9 | 2022-02-05 | Murrumbeena | | Toorak-Prahran Colts |
| 2/212 | | 60 E Hawkins 6/2 L Trojak Nyamuka 2/6 E Ward 2/11 A Brooks 3/5 T Langham 4/5 |
| 10 | 2022-02-12 | Clayton District | | Murrumbeena |
| 7/111 E Hawkins 2/9 | | 7/145 |
| 11 | 2022-02-19 | Toorak-Prahran Red | | Murrumbeena |
| 125 E Ward 3/3 B Bletsas 2/7 E Hawkins 2/13 | | 8/194 |
| 12 | 2022-02-26 | Murrumbeena | | Malvern Junior Gold |
| 7/153 | | 107 |
| 13 | 2022-03-05 | Toorak-Prahran - Blue | no play | Murrumbeena |
